BD-PT5061

BAGE5 Rabbit Polyclonal Antibody

BAG5; KIAA0873; BAG family molecular chaperone regulator 5; BAG-5; Bcl-2-associated athanogene 5

常规抗体

BAG5

BAG family molecular chaperone regulator 5

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

9529

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9529

Q9UL15

http://www.uniprot.org/uniprotkb/Q9UL15/entry

70369

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70369

Q8CI32

http://www.uniprot.org/uniprot/Q8CI32

366734

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=366734

Q5QJC9

http://www.uniprot.org/uniprot/Q5QJC9

Synthesized peptide derived from BAGE5 . at AA range: 30-110

BAGE5 Polyclonal Antibody detects endogenous levels of BAGE5 protein.

WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

51kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Brain,

nucleus,mitochondrion,cytosol,membrane,inclusion body,perinuclear region of cytoplasm,

function:Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2.,similarity:Contains 4 BAG domains.,subunit:Binds to the ATPase domain of HSP70/HSC chaperones. Binds PARK2.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.