产品名称
EF-1β Rabbit Polyclonal Antibody
别名
EEF1B2; EEF1B; EF1B; Elongation factor 1-beta; EF-1-beta
蛋白名称
Elongation factor 1-beta
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1933
Human Swissprot No.
P24534
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P24534/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55949
Mouse Swissprot No.
O70251
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70251
免疫原
The antiserum was produced against synthesized peptide derived from human EF-1beta. AA range:83-132
特异性
EF-1β Polyclonal Antibody detects endogenous levels of EF-1β protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR. [provided by RefSeq, Jul 2008],
组织表达
Brain,Epithelium,Eye,Fetal brain cortex,Keratinocyt
细胞定位
nucleus,cytoplasm,endoplasmic reticulum,cytosol,eukaryotic translation elongation factor 1 complex,
功能
function:EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.,PTM:Phosphorylation affects the GDP/GTP exchange rate.,similarity:Belongs to the EF-1-beta/EF-1-delta family.,similarity:Contains 1 GST C-terminal domain.,subunit:EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.