Cn|En

现货抗体产品库

ALDH3A1 Rabbit Polyclonal Antibody

产品详情 相关文献 产品问答 相关产品

产品基本信息

产品货号
BD-PT5025
产品名称
ALDH3A1 Rabbit Polyclonal Antibody
别名
ALDH3A1; ALDH3; Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHIII; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase family 3 member A1
类别
常规抗体
基因名称
ALDH3A1
蛋白名称
Aldehyde dehydrogenase dimeric NADP-preferring
推荐应用
WB
反应种属
Human,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
218
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=218
Human Swissprot No.
P30838
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P30838/entry
Mouse Swissprot No.
P47739
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P47739
Rat Gene ID
25375
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25375
Rat Swissprot No.
P11883
Rat Swissprot Link
http://www.uniprot.org/uniprot/P11883
免疫原
The antiserum was produced against synthesized peptide derived from human ALDH3A1. AA range:236-285
特异性
ALDH3A1 Polyclonal Antibody detects endogenous levels of ALDH3A1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
预测分子量
50kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008],
组织表达
High levels in stomach, esophagus and lung; low level in the liver and kidney.
细胞定位
Cytoplasm .
信号通路
Glycolysis / Gluconeogenesis;Histidine metabolism;Tyrosine metabolism;Phenylalanine metabolism;Metabolism of xenobiotics by cytochrome P450;Drug metabolism;
功能
catalytic activity:An aldehyde + NAD(P)(+) + H(2)O = an acid + NAD(P)H.,function:ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.,similarity:Belongs to the aldehyde dehydrogenase family.,subunit:Homodimer.,tissue specificity:High levels in stomach, esophagus and lung; low level in the liver and kidney.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from A549 cells, using ALDH3A1 antibody.

Western Blot analysis of extracts from A549, K562 cells, using ALDH3A1 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

相关文献

产品问答

相关产品

免责声明| 法律支持| 联系方式

市场:027-65023363   行政/人事:027-62439686   邮箱:marketing@brainvta.com  

销售总监:张经理  18995532642  华东区:陈经理 18013970337   华南区:王经理 13100653525   华中/西区:杨经理 18186518905   华北区:张经理 18893721749

地址:中国武汉东湖高新区光谷七路128号中科开物产业园1号楼

Copyright © 武汉枢密脑科学技术有限公司. All RIGHTS RESERVED.
鄂ICP备2021009124号 DIGITAL BY VTHINK