BD-PT5010

β-1,4-Gal-T5 Rabbit Polyclonal Antibody

B4GALT5; Beta-1; 4-galactosyltransferase 5; Beta-1,4-GalTase 5; Beta4Gal-T5; b4Gal-T5; Beta-1,4-GalT II; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5

常规抗体

B4GALT5

Beta-1,4-galactosyltransferase 5

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

9334

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9334

O43286

http://www.uniprot.org/uniprotkb/O43286/entry

56336

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56336

Q9JMK0

http://www.uniprot.org/uniprot/Q9JMK0

The antiserum was produced against synthesized peptide derived from human B4GALT5. AA range:321-370

β-1,4-Gal-T5 Polyclonal Antibody detects endogenous levels of β-1,4-Gal-T5 protein.

WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

40kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. This gene was previously designated as B4GALT4 but was renamed

Ubiquitously expressed.

Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein. Golgi apparatus . Trans cisternae of Golgi stack. .

O-Glycan biosynthesis;

cofactor:Manganese.,function:Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.,online information:Beta-1,4-galactosyltransferase 5,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 7 family.,subcellular location:Trans cisternae of Golgi stack.,tissue specificity:Ubiquitously expressed.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.