产品名称
α4Gn-T Rabbit Polyclonal Antibody
别名
A4GNT; Alpha-1; 4-N-acetylglucosaminyltransferase; Alpha4GnT
蛋白名称
Alpha-1,4-N-acetylglucosaminyltransferase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51146
Human Swissprot No.
Q9UNA3
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UNA3/entry
免疫原
The antiserum was produced against synthesized peptide derived from human A4GNT. AA range:31-80
特异性
α4Gn-T Polyclonal Antibody detects endogenous levels of α4Gn-T protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane. [provided by RefSeq, Jul 2008],
组织表达
Detected in stomach and pancreas.
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
功能
domain:The conserved DXD motif is involved in enzyme activity.,function:Necessary for the synthesis of type III mucin. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans.,online information:Alpha-1,4-N-acetylglucosaminyltransferase,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 32 family.,tissue specificity:Detected in stomach and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
