Cn|En

现货抗体产品库

ZP1 Rabbit Polyclonal Antibody

产品详情 相关文献 产品问答 相关产品

产品基本信息

产品货号
BD-PT4994
产品名称
ZP1 Rabbit Polyclonal Antibody
别名
ZP1; Zona pellucida sperm-binding protein 1; Zona pellucida glycoprotein 1; Zp-1
类别
常规抗体
基因名称
ZP1
蛋白名称
Zona pellucida sperm-binding protein 1
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
22917
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22917
Human Swissprot No.
P60852
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P60852/entry
Mouse Swissprot No.
Q62005
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q62005
免疫原
The antiserum was produced against synthesized peptide derived from human ZP1. AA range:221-270
特异性
ZP1 Polyclonal Antibody detects endogenous levels of ZP1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
预测分子量
70kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. [provided by RefSeq, May 2014],
组织表达
Expressed in oocytes (at protein level).
细胞定位
[Processed zona pellucida sperm-binding protein 1]: Zona pellucida .; Cell membrane ; Single-pass type I membrane protein .
功能
domain:The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.,function:The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida.,PTM:O-glycosylated.,PTM:Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.,similarity:Belongs to the ZP domain family. ZPB subfamily.,similarity:Contains 1 P-type (trefoil) domain.,similarity:Contains 1 ZP domain.,subunit:Polymers of ZP2 and ZP3 organized into long filaments cross-linked by ZP1 homodimers.,tissue specificity:Oocytes.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from LOVO cells, using ZP1 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HeLa cells using ZP1 antibody.

Western Blot analysis of LOVO cells using ZP1 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

相关文献

产品问答

相关产品

免责声明| 法律支持| 联系方式

市场:027-65023363   行政/人事:027-62439686   邮箱:marketing@brainvta.com  

销售总监:张经理  18995532642  华东区:陈经理 18013970337   华南区:王经理 13100653525   华中/西区:杨经理 18186518905   华北区:张经理 18893721749

地址:中国武汉东湖高新区光谷七路128号中科开物产业园1号楼

Copyright © 武汉枢密脑科学技术有限公司. All RIGHTS RESERVED.
鄂ICP备2021009124号 DIGITAL BY VTHINK