产品名称
ZNHIT1 Rabbit Polyclonal Antibody
别名
ZNHIT1; CGBP1; ZNFN4A1; Zinc finger HIT domain-containing protein 1; Cyclin-G1-binding protein 1; Zinc finger protein subfamily 4A member 1; p18 Hamlet
蛋白名称
Zinc finger HIT domain-containing protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10467
Human Swissprot No.
O43257
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O43257/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70103
Mouse Swissprot No.
Q8R331
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R331
免疫原
Synthesized peptide derived from ZNHIT1 . at AA range: 40-120
特异性
ZNHIT1 Polyclonal Antibody detects endogenous levels of ZNHIT1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Seems to play a role in p53-mediated apoptosis induction.,induction:Induced by DNA damage.,PTM:Phosphorylated on Thr by MAPK11 or MAPK14.,PTM:Stres-induced ZNHIT1 is mainly regulated at the level of protein.,similarity:Belongs to the ZNHIT1 family.,similarity:Contains 1 HIT-type zinc finger.,subunit:Interacts with MAPK11 and MAPK14. Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1.,
组织表达
Expressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine.
功能
function:Seems to play a role in p53-mediated apoptosis induction.,induction:Induced by DNA damage.,PTM:Phosphorylated on Thr by MAPK11 or MAPK14.,PTM:Stres-induced ZNHIT1 is mainly regulated at the level of protein.,similarity:Belongs to the ZNHIT1 family.,similarity:Contains 1 HIT-type zinc finger.,subunit:Interacts with MAPK11 and MAPK14. Component of the chromatin-remodeling SRCAP complex composed of at least SRCAP, DMAP1, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
