产品名称
ZNF592 Rabbit Polyclonal Antibody
别名
ZNF592; KIAA0211; Zinc finger protein 592
蛋白名称
Zinc finger protein 592
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9640
Human Swissprot No.
Q92610
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q92610/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=233410
Mouse Swissprot No.
Q8BHZ4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BHZ4
免疫原
The antiserum was produced against synthesized peptide derived from human ZNF592. AA range:961-1010
特异性
ZNF592 Polyclonal Antibody detects endogenous levels of ZNF592 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
zinc finger protein 592(ZNF592) Homo sapiens This gene is thought to play a role in a complex developmental pathway and the regulation of genes involved in cerebellar development. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia. [provided by RefSeq, Jan 2011],
组织表达
Widely expressed, with highest levels in skeletal muscle. Expressed throughout the central nervous system, including in the cerebellum and cerebellar vermis, with higher expression in the substantia nigra. Widely expressed in fetal tissues.
功能
function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 13 C2H2-type zinc fingers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
