产品名称
ZNF460 Rabbit Polyclonal Antibody
别名
ZNF460; ZNF272; Zinc finger protein 460; Zinc finger protein 272; Zinc finger protein HZF8
蛋白名称
Zinc finger protein 460
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10794
Human Swissprot No.
Q14592
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q14592/entry
免疫原
The antiserum was produced against synthesized peptide derived from human ZNF460. AA range:461-510
特异性
ZNF460 Polyclonal Antibody detects endogenous levels of ZNF460 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
zinc finger protein 460(ZNF460) Homo sapiens Zinc finger proteins, such as ZNF272, interact with nucleic acids and have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See ZFP93 (MIM 604749) for additional information on zinc finger proteins.[supplied by OMIM, May 2004],
组织表达
Ubiquitously expressed at low levels. Highest levels are found in pancreas and liver.
功能
function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 11 C2H2-type zinc fingers.,tissue specificity:Ubiquitously expressed at low levels. Highest levels are found in pancreas and liver.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
