BD-PT4965-ZNF420 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

ZNF420 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT4965

产品名称

ZNF420 Rabbit Polyclonal Antibody

别名

ZNF420; Zinc finger protein 420

类别

常规抗体

基因名称

ZNF420

蛋白名称

Zinc finger protein 420

推荐应用

反应种属

Human,Mouse

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

147923

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=147923

Human Swissprot No.

Q8TAQ5

Human Swissprot Link

http://www.uniprot.org/uniprotkb/Q8TAQ5/entry

免疫原

The antiserum was produced against synthesized peptide derived from human ZNF420. AA range:301-350

特异性

ZNF420 Polyclonal Antibody detects endogenous levels of ZNF420 protein.

稀释度

WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

预测分子量

80kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

zinc finger protein 420(ZNF420) Homo sapiens The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016],

组织表达

Muscle,Placenta,Testis,

细胞定位

Nucleus .

功能

function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 KRAB domain.,similarity:Contains 19 C2H2-type zinc fingers.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of ZNF420 Antibody. The lane on the right is blocked with the ZNF420 peptide.

Western blot analysis of the lysates from COLO205 cells using ZNF420 antibody.

Western Blot analysis of K562 cells using ZNF420 Polyclonal Antibody. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit （SC-003,Inventbiotech,MN,USA）.