产品名称
ZIP7 Rabbit Polyclonal Antibody
别名
SLC39A7; HKE4; RING5; Zinc transporter SLC39A7; Histidine-rich membrane protein Ke4; Really interesting new gene 5 protein; Solute carrier family 39 member 7
蛋白名称
Zinc transporter SLC39A7
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7922
Human Swissprot No.
Q92504
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q92504/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=14977
Mouse Swissprot No.
Q31125
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q31125
免疫原
The antiserum was produced against synthesized peptide derived from human SLC39A7. AA range:131-180
特异性
ZIP7 Polyclonal Antibody detects endogenous levels of ZIP7 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus, cis-Golgi network membrane ; Multi-pass membrane protein .
功能
similarity:Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.,tissue specificity:Major expression in placenta, lung, kidney and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
