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ZIP1 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT4947
产品名称
ZIP1 Rabbit Polyclonal Antibody
别名
SLC39A1; IRT1; ZIP1; ZIRTL; CGI-08; CGI-71; Zinc transporter ZIP1; Solute carrier family 39 member 1; Zinc-iron-regulated transporter-like; Zrt- and Irt-like protein 1; ZIP-1; hZIP1
类别
常规抗体
基因名称
SLC39A1
蛋白名称
Zinc transporter ZIP1
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
27173
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27173
Human Swissprot No.
Q9NY26
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NY26/entry
Mouse Swissprot No.
Q9QZ03
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9QZ03
免疫原
The antiserum was produced against synthesized peptide derived from human SLC39A1. AA range:111-160
特异性
ZIP1 Polyclonal Antibody detects endogenous levels of ZIP1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
预测分子量
38kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the zinc-iron permease family. The encoded protein is localized to the cell membrane and acts as a zinc uptake transporter. This gene has been linked to prostate cancer, breast cancer, and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],
组织表达
Ubiquitous. Expressed in most adult and fetal tissues including the epidermis.
细胞定位
Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines.
功能
function:Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells.,miscellaneous:Inhibited by Ni(2+) ions. Fe(2+) ions do not inhibit zinc uptake.,similarity:Belongs to the ZIP transporter (TC 2.A.5) family.,subcellular location:Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines.,tissue specificity:Ubiquitous. Expressed in most adult and fetal tissues including the epidermis.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from Jurkat cells, using SLC39A1 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from COLO205 cells using SLC39A1 antibody.

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