产品名称
ZFYVE19 Rabbit Polyclonal Antibody
别名
ZFYVE19; MPFYVE; Zinc finger FYVE domain-containing protein 19; MLL partner containing FYVE domain
蛋白名称
Zinc finger FYVE domain-containing protein 19
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84936
Human Swissprot No.
Q96K21
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96K21/entry
Mouse Swissprot No.
Q9DAZ9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9DAZ9
免疫原
The antiserum was produced against synthesized peptide derived from human ZFYVE19. AA range:311-360
特异性
ZFYVE19 Polyclonal Antibody detects endogenous levels of ZFYVE19 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver.,
组织表达
Detected in brain, heart, skeletal muscle, kidney and liver.
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cleavage furrow . Midbody, Midbody ring . Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis. .
功能
disease:A chromosomal aberration involving ZFYVE19 is associated with acute myeloblastic leukemia (AML). Translocation t(11;15)(q23;q14) with MLL/HRX.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,tissue specificity:Detected in brain, heart, skeletal muscle, kidney and liver.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
