产品名称
ABT1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/29777
Human Swissprot No.
Q9ULW3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9ULW3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/30946
Mouse Swissprot No.
Q9QYL7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9QYL7
Rat Gene Link
https://www.uniprot.org/uniprot/306960
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4KLM5
免疫原
Synthesized peptide derived from human ABT1 AA range: 140-190
特异性
This antibody detects endogenous levels of ABT1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus, nucleolus .
功能
function:Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes.,similarity:Belongs to the ESF2/ABP1 family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with ESF1/ABTAP.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.