产品名称
DPYL3 Rabbit Polyclonal Antibody
别名
Dihydropyrimidinase-related protein 3 (DRP-3) (Collapsin response mediator protein 4) (CRMP-4) (Unc-33-like phosphoprotein 1) (ULIP-1)
基因名称
DPYSL3 CRMP4 DRP3 ULIP ULIP1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.179% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1809
Human Swissprot No.
Q14195
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q14195/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/22240
Mouse Swissprot No.
Q62188
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q62188
Rat Gene Link
https://www.uniprot.org/uniprot/25418
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q62952
免疫原
Synthesized peptide derived from human DPYL3 AA range: 240-290
特异性
This antibody detects endogenous levels of DPYL3 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
细胞定位
Cytoplasm . Cell projection, growth cone . Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. .
功能
function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subcellular location:Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL4 or DPYSL5 (By similarity). Interacts with synaptic vesicle protein 2 and SH3A domain of intersectin.,tissue specificity:Mainly in heart and skeletal muscle. Also expressed strongly in fetal brain and spinal cord.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
