产品名称
XE7 Rabbit Polyclonal Antibody
别名
AKAP17A; CXYorf3; DXYS155E; SFRS17A; XE7; A-kinase anchor protein 17A; AKAP-17A; 721P; B-lymphocyte antigen; Protein XE7; Protein kinase A-anchoring protein 17A; PRKA17A; Splicing factor; arginine/serine-rich 17A
蛋白名称
A-kinase anchor protein 17A
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8227
Human Swissprot No.
Q02040
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q02040/entry
免疫原
Synthesized peptide derived from XE7 . at AA range: 590-670
特异性
XE7 Polyclonal Antibody detects endogenous levels of XE7 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
A-kinase anchoring protein 17A(AKAP17A) Homo sapiens This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010],
组织表达
Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B-cells and placenta. Expressed in all cell lines tested including Jurkat-TAg, U-937 and HEK293 cells.
功能
caution:Was originally (PubMed:1438229) thought to be a cell surface protein involved in B-cell activation.,function:Splice factor regulating alternative splice site selection for certain mRNA precursors.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Monomer. Component of the spliceosome. Interacts with ZRANB2 and SFRS1/ASF through its Arg/Ser-rich domain.,tissue specificity:Widely expressed. Found in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Expressed in activated B-cells and placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
