产品名称
v-SNARE Vti1p Rabbit Polyclonal Antibody
别名
VTI1B; VTI1; VTI1L; VTI1L1; VTI2; Vesicle transport through interaction with t-SNAREs homolog 1B; Vesicle transport v-SNARE protein Vti1-like 1; Vti1-rp1
蛋白名称
Vesicle transport through interaction with t-SNAREs homolog 1B
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10490
Human Swissprot No.
Q9UEU0
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UEU0/entry
Mouse Swissprot No.
O88384
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O88384
Rat Swissprot Link
http://www.uniprot.org/uniprot/P58200
免疫原
Synthesized peptide derived from the Internal region of human v-SNARE Vti1p.
特异性
v-SNARE Vti1p Polyclonal Antibody detects endogenous levels of v-SNARE Vti1p protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.,similarity:Belongs to the VTI1 family.,subunit:Found in a complex with VAMP8 and STX7 in the liver. Forms a SNARE complex with STX7, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Part of the SNARE core complex containing STX7, STX8 and VAMP8.,tissue specificity:Expressed in all tissues examined.,
组织表达
Expressed in all tissues examined.
细胞定位
Early endosome membrane ; Single-pass type IV membrane protein . Late endosome membrane ; Single-pass type IV membrane protein . Lysosome membrane . Cytoplasmic granule . Recycling endosome membrane ; Single-pass type IV membrane protein .
信号通路
SNARE interactions in vesicular transport;
功能
function:V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.,similarity:Belongs to the VTI1 family.,subunit:Found in a complex with VAMP8 and STX7 in the liver. Forms a SNARE complex with STX7, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Part of the SNARE core complex containing STX7, STX8 and VAMP8.,tissue specificity:Expressed in all tissues examined.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.