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VPS26B Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT4889
产品名称
VPS26B Rabbit Polyclonal Antibody
别名
VPS26B; Vacuolar protein sorting-associated protein 26B; Vesicle protein sorting 26B
类别
常规抗体
基因名称
VPS26B
蛋白名称
Vacuolar protein sorting-associated protein 26B
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
112936
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=112936
Human Swissprot No.
Q4G0F5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q4G0F5/entry
Mouse Gene ID
69091
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69091
Mouse Swissprot No.
Q8C0E2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8C0E2
免疫原
The antiserum was produced against synthesized peptide derived from human VPS26B. AA range:231-280
特异性
VPS26B Polyclonal Antibody detects endogenous levels of VPS26B protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
预测分子量
45kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
组织表达
Eye,Lung,Placenta,
细胞定位
Cytoplasm . Membrane; Peripheral membrane protein . Early endosome . Late endosome . Localizes to early and late endosomal structures (By similarity). .
功能
function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from LOVO cells, using VPS26B Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of LOVO cells using VPS26B Polyclonal Antibody. Secondary antibody was diluted at 1:20000

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