产品名称
VHX Rabbit Polyclonal Antibody
别名
DUSP22; JSP1; LMWDSP2; MKPX; Dual specificity protein phosphatase 22; JNK-stimulatory phosphatase-1; JSP-1; Low molecular weight dual specificity phosphatase 2; LMW-DSP2; Mitogen-activated protein kinase phosphatase x; MAP kinase phosphatas
蛋白名称
Dual specificity protein phosphatase 22
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56940
Human Swissprot No.
Q9NRW4
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NRW4/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=105352
Mouse Swissprot No.
Q99N11
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99N11
免疫原
The antiserum was produced against synthesized peptide derived from human DUSP22. AA range:121-170
特异性
VHX Polyclonal Antibody detects endogenous levels of VHX protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK).,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.,
组织表达
Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.
功能
catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK).,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
