BD-PM3063

Kif 7(3F8)Mouse Monoclonal Antibody

Kinesin-like protein KIF7

常规抗体

KIF7

Kinesin-like protein KIF7

WB

Human,Mouse,Rat

PBS, pH 7.4, containing 0.5%BSA, 0.02% New type preservative N as Preservative and 50% Glycerol.

374654

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=374654

Q2M1P5

http://www.uniprot.org/uniprotkb/Q2M1P5/entry

16576

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16576

B7ZNG0

http://www.uniprot.org/uniprot/B7ZNG0

http://www.uniprot.org/uniprot/

Synthetic Peptide of Kif 7

The antibody detects endogenous Kif 7 proteins.

WB 500-2000 1:200 IF 1:50-200

-20°C/1 year

Monoclonal, Mouse

This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011],

Embryonic stem cells, melanotic melanoma and Jurkat T-cells. Expressed in heart, lung, liver, kidney, testis, retina, placenta, pancreas, colon, small intestin, prostate and thymus.

Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Localizes to the cilium tip.

similarity:Belongs to the kinesin-like protein family. KIF27 subfamily.,similarity:Contains 1 kinesin-motor domain.,tissue specificity:Embryonic stem cells, melanotic melanoma and Jurkat T-cells.,

现货

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.