产品名称
USP40 Rabbit Polyclonal Antibody
别名
USP40; Ubiquitin carboxyl-terminal hydrolase 40; Deubiquitinating enzyme 40; Ubiquitin thioesterase 40; Ubiquitin-specific-processing protease 40
蛋白名称
Ubiquitin carboxyl-terminal hydrolase 40
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55230
Human Swissprot No.
Q9NVE5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NVE5/entry
Mouse Swissprot No.
Q8BWR4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BWR4
免疫原
The antiserum was produced against synthesized peptide derived from human USP40. AA range:1011-1060
特异性
USP40 Polyclonal Antibody detects endogenous levels of USP40 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],
功能
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May be catalytically inactive.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Broadly expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.