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USP40 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT4838
产品名称
USP40 Rabbit Polyclonal Antibody
别名
USP40; Ubiquitin carboxyl-terminal hydrolase 40; Deubiquitinating enzyme 40; Ubiquitin thioesterase 40; Ubiquitin-specific-processing protease 40
类别
常规抗体
基因名称
USP40
蛋白名称
Ubiquitin carboxyl-terminal hydrolase 40
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
55230
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55230
Human Swissprot No.
Q9NVE5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NVE5/entry
Mouse Swissprot No.
Q8BWR4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BWR4
免疫原
The antiserum was produced against synthesized peptide derived from human USP40. AA range:1011-1060
特异性
USP40 Polyclonal Antibody detects endogenous levels of USP40 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
预测分子量
140kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],
组织表达
Broadly expressed.
细胞定位
nucleus,cytoplasm,
功能
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May be catalytically inactive.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Broadly expressed.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using USP40 Antibody. The picture on the right is blocked with the synthesized peptide.

Western Blot analysis of 293 cells using USP40 Polyclonal Antibody diluted at 1:500. Secondary antibody was diluted at 1:20000

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