产品名称
USP36 Rabbit Polyclonal Antibody
别名
USP36; KIAA1453; Ubiquitin carboxyl-terminal hydrolase 36; Deubiquitinating enzyme 36; Ubiquitin thioesterase 36; Ubiquitin-specific-processing protease 36
蛋白名称
Ubiquitin carboxyl-terminal hydrolase 36
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57602
Human Swissprot No.
Q9P275
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9P275/entry
Mouse Swissprot No.
B1AQJ2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/B1AQJ2
免疫原
The antiserum was produced against synthesized peptide derived from human USP36. AA range:501-550
特异性
USP36 Polyclonal Antibody detects endogenous levels of USP36 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the peptidase C19 or ubiquitin-specific protease family of cysteine proteases. Members of this family remove ubiquitin molecules from polyubiquitinated proteins. The encoded protein may deubiquitinate and stabilize the transcription factor c-Myc, also known as MYC, an important oncoprotein known to be upregulated in most human cancers. The encoded protease may also regulate the activation of autophagy. This gene exhibits elevated expression in some breast and lung cancers. [provided by RefSeq, Mar 2016],
细胞定位
Nucleus, nucleolus . Cytoplasm .
功能
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Broadly expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.