产品名称
USP30 Rabbit Polyclonal Antibody
别名
USP30; Ubiquitin carboxyl-terminal hydrolase 30; Deubiquitinating enzyme 30; Ubiquitin thioesterase 30; Ubiquitin-specific-processing protease 30; Ub-specific protease 30
蛋白名称
Ubiquitin carboxyl-terminal hydrolase 30
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84749
Human Swissprot No.
Q70CQ3
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q70CQ3/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100756
Mouse Swissprot No.
Q3UN04
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UN04
免疫原
The antiserum was produced against synthesized peptide derived from human USP30. AA range:31-80
特异性
USP30 Polyclonal Antibody detects endogenous levels of USP30 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
预测分子量
60kd,unspecial bands( 65kd,105kd,130kd)in Hela and HCT116 cell.
宿主
Polyclonal, Rabbit,IgG
背景介绍
USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 [PubMed 18287522]).[supplied by OMIM, Dec 2008],
组织表达
Expressed in skeletal muscle, pancreas, liver and kidney.
细胞定位
Mitochondrion outer membrane .
功能
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May participate in the maintenance of mitochondrial morphology.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in skeletal muscle, pancreas, liver and kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
