产品名称
USP19 Rabbit Polyclonal Antibody
别名
USP19; KIAA0891; ZMYND9; Ubiquitin carboxyl-terminal hydrolase 19; Deubiquitinating enzyme 19; Ubiquitin thioesterase 19; Ubiquitin-specific-processing protease 19; Zinc finger MYND domain-containing protein 9
蛋白名称
Ubiquitin carboxyl-terminal hydrolase 19
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10869
Human Swissprot No.
O94966
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O94966/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=71472
Mouse Swissprot No.
Q3UJD6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UJD6
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=361190
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q6J1Y9
免疫原
The antiserum was produced against synthesized peptide derived from human USP19. AA range:391-440
特异性
USP19 Polyclonal Antibody detects endogenous levels of USP19 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 2 CS domains.,
组织表达
Brain,Epithelium,Skin,Testis,
细胞定位
Endoplasmic reticulum membrane ; Single-pass membrane protein .
功能
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 2 CS domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.