产品名称
AKIR2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55122
Human Swissprot No.
Q53H80
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q53H80/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/433693
Mouse Swissprot No.
B1AXD8
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/B1AXD8
Rat Gene Link
https://www.uniprot.org/uniprot/297968
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q25C79
免疫原
Synthesized peptide derived from human AKIR2 AA range: 14-64
特异性
This antibody detects endogenous levels of AKIR2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
组织表达
Widely expressed with the highest expression in peripheral blood leukocytes.
细胞定位
Nucleus . Cytoplasm . Membrane . Present mainly in the nuclear fraction, and at much lower level in the cytoplasmic and membrane fractions. .
功能
function:Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1.,miscellaneous:'Akiraka ni suru' means 'making things clear' in Japanese. The name is given based on the presence of the clear nuclear localization signal.,similarity:Belongs to the akirin family.,subunit:Interacts with YWHAB.,tissue specificity:Widely expressed with the highest expression in peripheral blood leukocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
