产品名称
UMP-CMP Kinase Rabbit Polyclonal Antibody
别名
CMPK1; CMK; CMPK; UCK; UMK; UMPK; UMP-CMP kinase; Cytidine monophosphate kinase; Cytidylate kinase; Deoxycytidylate kinase; Uridine monophosphate kinase; Uridine monophosphate/cytidine monophosphate kinase; UMP/CMP kinase; UMP/CMPK
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51727
Human Swissprot No.
P30085
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P30085/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66588
Mouse Swissprot No.
Q9DBP5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9DBP5
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=298410
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q4KM73
免疫原
The antiserum was produced against synthesized peptide derived from human KCY. AA range:1-50
特异性
UMP-CMP Kinase Polyclonal Antibody detects endogenous levels of UMP-CMP Kinase protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012],
组织表达
Ubiquitously expressed.
细胞定位
Nucleus . Cytoplasm . Predominantly cytoplasmic, less than 15% nuclear. .
信号通路
Pyrimidine metabolism;
功能
catalytic activity:ATP + (d)CMP = ADP + (d)CDP.,cofactor:Magnesium.,function:Catalyzes specific phosphoryl transfer from ATP to UMP and CMP.,similarity:Belongs to the adenylate kinase family.,subcellular location:Mainly nuclear.,tissue specificity:Ubiquitously expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
