产品名称
UBCE7IP4 Rabbit Polyclonal Antibody
别名
RNF144A; KIAA0161; RNF144; UBCE7IP4; Probable E3 ubiquitin-protein ligase RNF144A; RING finger protein 144A; UbcM4-interacting protein 4; Ubiquitin-conjugating enzyme 7-interacting protein 4
蛋白名称
Probable E3 ubiquitin-protein ligase RNF144A
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9781
Human Swissprot No.
P50876
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P50876/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=108089
Mouse Swissprot No.
Q925F3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q925F3
免疫原
The antiserum was produced against synthesized peptide derived from human RNF144A. AA range:151-200
特异性
UBCE7IP4 Polyclonal Antibody detects endogenous levels of UBCE7IP4 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this protein contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The mouse counterpart of this protein has been shown to interact with Ube2l3/UbcM4, which is an ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass membrane protein . Cytoplasmic vesicle membrane .
功能
caution:Lacks the His residue in the RING-type domain 2 that is one of the conserved features of the family.,function:E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the RBR family. RNF144 subfamily.,similarity:Contains 1 IBR-type zinc finger.,similarity:Contains 2 RING-type zinc fingers.,subunit:Interacts with UBE2L3.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
