产品名称
Uba5 Rabbit Polyclonal Antibody
别名
UBA5; UBE1DC1; Ubiquitin-like modifier-activating enzyme 5; Ubiquitin-activating enzyme 5; ThiFP1; UFM1-activating enzyme; Ubiquitin-activating enzyme E1 domain-containing protein 1
蛋白名称
Ubiquitin-like modifier-activating enzyme 5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79876
Human Swissprot No.
Q9GZZ9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9GZZ9/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66663
Mouse Swissprot No.
Q8VE47
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8VE47
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=300968
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5M7A4
免疫原
The antiserum was produced against synthesized peptide derived from human UBA5. AA range:281-330
特异性
Uba5 Polyclonal Antibody detects endogenous levels of Uba5 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been identified on chromosome 1. [provided by RefSeq, Feb 2016],
细胞定位
Cytoplasm . Nucleus . Endoplasmic reticulum membrane . Golgi apparatus . Localizes mainly in the cytoplasm, while it localizes to the nucleus in presence of SUMO2 (PubMed:18442052). Interaction with GABARAPL2 promotes localization to the endoplasmic reticulum membrane (PubMed:30990354). .
功能
function:E1-like enzyme which activates UFM1.,similarity:Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
