产品名称
TWIK-3 Rabbit Polyclonal Antibody
别名
KCNK7; Potassium channel subfamily K member 7
蛋白名称
Potassium channel subfamily K member 7
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10089
Human Swissprot No.
Q9Y2U2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y2U2/entry
Mouse Swissprot No.
Q9Z2T1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9Z2T1
免疫原
Synthesized peptide derived from TWIK-3 . at AA range: 170-250
特异性
TWIK-3 Polyclonal Antibody detects endogenous levels of TWIK-3 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Brain,PCR rescued clones,
细胞定位
Membrane ; Multi-pass membrane protein .
功能
function:Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
