BD-PT4783-TUSC2 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

TUSC2 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT4783

产品名称

TUSC2 Rabbit Polyclonal Antibody

别名

TUSC2; C3orf11; FUS1; LGCC; PDAP2; Tumor suppressor candidate 2; Fusion 1 protein; Fus-1 protein; PDGFA-associated protein 2

类别

常规抗体

基因名称

TUSC2

蛋白名称

Tumor suppressor candidate 2

推荐应用

反应种属

Human,Mouse

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

11334

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11334

Human Swissprot No.

O75896

Human Swissprot Link

http://www.uniprot.org/uniprotkb/O75896/entry

Mouse Gene ID

80385

Mouse Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80385

Mouse Swissprot No.

Q9WVF8

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q9WVF8

免疫原

The antiserum was produced against synthesized peptide derived from human TUSC2. AA range:41-90

特异性

TUSC2 Polyclonal Antibody detects endogenous levels of TUSC2 protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

预测分子量

12kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008],

组织表达

Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.

细胞定位

mitochondrion,

功能

function:May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.,PTM:Myristoylation is required for tumor suppressor activity.,similarity:Belongs to the TUSC2 family.,tissue specificity:Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from HeLa cells, using TUSC2 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of 293T cells using TUSC2 Polyclonal Antibody diluted at 1：1000. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded Human heart. Antibody was diluted at 1:100（4°,overnight）. High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl （right） obtaned from antibody was pre-absorbed by immunogen peptide.