产品名称
ZN268 Rabbit Polyclonal Antibody
别名
Zinc finger protein 268 (Zinc finger protein HZF3)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.196% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/10795
Human Swissprot No.
Q14587
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q14587/entry
免疫原
Synthesized peptide derived from human ZN268 AA range: 201-251
特异性
This antibody detects endogenous levels of ZN268 at Human
宿主
Polyclonal, Rabbit,IgG
组织表达
Overexpressed in ovarian cancer tissues compared to normal ovarian tissues. Isoform 1 and isoform 2 are expressed in squamous epithelium tissues. Isoform 2 is overexpressed in squamous cervical cancer (at protein level). Expressed in blood cells. Isoform 1 is expressed in pancreas, lung, skeletal muscle, heart, placenta, liver, kidney and brain. Isoform 2 expressed in chronic lymphocytic leukemia (CLL) and several tumor cell lines. Isoform 3 is expressed in several tumor cells. Isoform 5 is expressed in fetal liver and several tumor cells. Isoform 6 is weakly expressed in brain, lung amd small intestin and in several tumor cells. Isoform 7 is expressed in fetal liver and several tumor cells.
细胞定位
[Isoform 1]: Nucleus .; [Isoform 2]: Nucleus . Cytoplasm .
功能
developmental stage:Highly expressed in 3- to 5-week-old embryos.,function:May be involved in transcriptional regulation.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 24 C2H2-type zinc fingers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
