产品名称
TSSC1 Rabbit Polyclonal Antibody
别名
TSSC1; Protein TSSC1; Tumor-suppressing STF cDNA 1 protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein
反应种属
Human,Mouse,Rat,Monkey
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7260
Human Swissprot No.
Q53HC9
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q53HC9/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=380752
Mouse Swissprot No.
Q8K0G5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K0G5
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362721
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5PPK9
免疫原
The antiserum was produced against synthesized peptide derived from human TSSC1. AA range:291-340
特异性
TSSC1 Polyclonal Antibody detects endogenous levels of TSSC1 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11. [provided by RefSeq, Dec 2008],
细胞定位
Golgi apparatus, trans-Golgi network .
功能
similarity:Contains 5 WD repeats.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.