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Trypsin-3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT4754
产品名称
Trypsin-3 Rabbit Polyclonal Antibody
别名
PRSS3; PRSS4; TRY3; TRY4; Trypsin-3; Brain trypsinogen; Mesotrypsinogen; Serine protease 3; Serine protease 4; Trypsin III; Trypsin IV
类别
常规抗体
基因名称
PRSS3
蛋白名称
Trypsin-3
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
5646
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5646
Human Swissprot No.
P35030
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P35030/entry
免疫原
The antiserum was produced against synthesized peptide derived from human Trypsin-3. AA range:117-166
特异性
Trypsin-3 Polyclonal Antibody detects endogenous levels of Trypsin-3 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
预测分子量
32kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010],
组织表达
Detected in pancreas and pancreatic fluid (at protein level) (PubMed:6698368). Expressed in pancreas and brain (PubMed:8294000). Detected in ileum (PubMed:12021776).
细胞定位
Secreted .
信号通路
Neuroactive ligand-receptor interaction;
功能
catalytic activity:Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.,cofactor:Binds 1 calcium ion per subunit.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Pancreas and brain.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysate from A549 cells, using Trypsin-3 antibody.

Western Blot analysis of various cells using Trypsin-3 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

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