BD-PT4747

Troponin I-C Rabbit Polyclonal Antibody

TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I

常规抗体

TNNI3

Troponin I cardiac muscle

WB

Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

21954

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21954

29248

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29248

P23693

http://www.uniprot.org/uniprot/P23693

The antiserum was produced against synthesized peptide derived from mouse TNNI3. AA range:5-54

Troponin I-C Polyclonal Antibody detects endogenous levels of Troponin I-C protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

28kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.