产品名称
TRH-R1 Rabbit Polyclonal Antibody
别名
TRHR; Thyrotropin-releasing hormone receptor; TRH-R; Thyroliberin receptor
蛋白名称
Thyrotropin-releasing hormone receptor
反应种属
Human,Mouse,Rat,Monkey
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7201
Human Swissprot No.
P34981
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P34981/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22045
Mouse Swissprot No.
P21761
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P21761
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25570
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q01717
免疫原
The antiserum was produced against synthesized peptide derived from human TRHR. AA range:195-244
特异性
TRH-R1 Polyclonal Antibody detects endogenous levels of TRH-R1 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011],
组织表达
Brain,Pituitary,Placenta,
细胞定位
Cell membrane ; Multi-pass membrane protein .
信号通路
Calcium;Neuroactive ligand-receptor interaction;
功能
function:Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
