产品名称
FLVC2 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55640
Human Swissprot No.
Q9UPI3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UPI3/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/217721
Mouse Swissprot No.
Q91X85
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91X85
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P60815
免疫原
Synthesized peptide derived from human FLVC2 AA range: 352-402
特异性
This antibody detects endogenous levels of FLVC2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Aug 2010],
组织表达
Expressed in non-hematopoietic tissues, with relative abundant expression in brain, placenta, lung, liver and kidney. Also expressed in hematopoietic tissues (fetal liver, spleen, lymph node, thymus, leukocytes and bone marrow). Found in acidophil cells of the pituitary that secrete growth hormone and prolactin.
细胞定位
Cell membrane; Multi-pass membrane protein.
功能
function:Transporter specific for a calcium-chelator complex, important for growth and calcium metabolism.,similarity:Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family.,tissue specificity:Found in acidophil cells of the pituitary that secrete growth hormone and prolactin.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
