BD-PT4713-Tra-2α Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

Tra-2α Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT4713

产品名称

Tra-2α Rabbit Polyclonal Antibody

别名

TRA2A; Transformer-2 protein homolog alpha; TRA-2 alpha; TRA2-alpha; Transformer-2 protein homolog A

类别

常规抗体

基因名称

TRA2A

蛋白名称

Transformer-2 protein homolog alpha

推荐应用

反应种属

Human,Mouse

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

29896

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29896

Human Swissprot No.

Q13595

Human Swissprot Link

http://www.uniprot.org/uniprotkb/Q13595/entry

Mouse Swissprot No.

Q6PFR5

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q6PFR5

免疫原

The antiserum was produced against synthesized peptide derived from human TRA-2 alpha. AA range:221-270

特异性

Tra-2α Polyclonal Antibody detects endogenous levels of Tra-2α protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

预测分子量

33kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013],

组织表达

Cervix carcinoma,Epithelium,Hepatocyte,Lung,Testis,Uterus,

细胞定位

Nucleus .

信号通路

Spliceosome;

功能

function:Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.,PTM:Phosphorylated in the RS domains.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Binds to A3 enhancer proteins SRp75, SRp55, SRp40 and SRp30.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of HeLa cells, using TRA-2 alpha Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TRA-2 alpha Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from HUVEC cells, using TRA-2 alpha Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using Tra-2α Polyclonal Antibody diluted at 1：500. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit （SC-003,Inventbiotech,MN,USA）.