产品名称
TNF-IP 1 Rabbit Polyclonal Antibody
别名
TNFAIP1; BACURD2; EDP1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; hBACURD2; BTB/POZ domain-containing protein TNFAIP1; Protein B12; Tumor necrosis factor; alpha-induced protein 1, endothelial
蛋白名称
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7126
Human Swissprot No.
Q13829
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q13829/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21927
Mouse Swissprot No.
O70479
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70479
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=287543
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q7TNY1
免疫原
The antiserum was produced against synthesized peptide derived from human TNAP1. AA range:71-120
特异性
TNF-IP 1 Polyclonal Antibody detects endogenous levels of TNF-IP 1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq, Jul 2008],
组织表达
Amygdala,Endothelial cell,Epithelium,Lung,
细胞定位
Cytoplasm. Nucleus. Endosome. Colocalizes with RHOB in endosomes.
功能
function:Enhances the PCNA-dependent DNA polymerase delta activity.,induction:By TNF-alpha, interleukin-1 beta and lipopolysaccharide (LPS).,similarity:Belongs to the KCTD10/KCTD13/TNFAIP1 family.,similarity:Contains 1 BTB (POZ) domain.,subunit:Interacts with PCNA.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
