产品名称
MMRN2 Rabbit Polyclonal Antibody
别名
Multimerin-2 (EMILIN-3) (Elastin microfibril interface located protein 3) (Elastin microfibril interfacer 3) (EndoGlyx-1 p125/p140 subunit)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.204% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/79812
Human Swissprot No.
Q9H8L6
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H8L6/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/105450
Mouse Swissprot No.
A6H6E2
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/A6H6E2
免疫原
Synthesized peptide derived from human MMRN2 AA range: 133-183
特异性
This antibody detects endogenous levels of MMRN2 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6. [provided by RefSeq, Aug 2012],
细胞定位
Secreted, extracellular space, extracellular matrix .
功能
PTM:N- and O-glycosylated.,similarity:Contains 1 C1q domain.,similarity:Contains 1 EMI domain.,subunit:Heteromer of p110, p125, p140 and p200 subunits; disulfide-linked.,tissue specificity:Endothelium.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
