BD-PT4678

TMEM145 Rabbit Polyclonal Antibody

TMEM145; Transmembrane protein 145

常规抗体

TMEM145

Transmembrane protein 145

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

284339

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=284339

Q8NBT3

http://www.uniprot.org/uniprotkb/Q8NBT3/entry

330485

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=330485

Q8C4U2

http://www.uniprot.org/uniprot/Q8C4U2

The antiserum was produced against synthesized peptide derived from human TMEM145. AA range:58-107

TMEM145 Polyclonal Antibody detects endogenous levels of TMEM145 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

56kD

-20°C/1 year

Polyclonal, Rabbit,IgG

TMEM145 (transmembrane protein 145) is a 493 amino acid protein encoded by a gene mapping to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.

Retinoblastoma,

Membrane ; Multi-pass membrane protein .

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.