产品名称
TFIIIC110 Rabbit Polyclonal Antibody
别名
GTF3C2; KIAA0011; General transcription factor 3C polypeptide 2; TF3C-beta; Transcription factor IIIC 110 kDa subunit; TFIIIC 110 kDa subunit; TFIIIC110; Transcription factor IIIC subunit beta
蛋白名称
General transcription factor 3C polypeptide 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2976
Human Swissprot No.
Q8WUA4
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8WUA4/entry
Mouse Swissprot No.
Q8BL74
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BL74
免疫原
The antiserum was produced against synthesized peptide derived from human TF3C2. AA range:71-120
特异性
TFIIIC110 Polyclonal Antibody detects endogenous levels of TFIIIC110 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.,similarity:Contains 4 WD repeats.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6.,
组织表达
Bone marrow,Brain,Colon,Epithelium,
功能
function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.,similarity:Contains 4 WD repeats.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
