产品名称
Tetraspanin-8 Rabbit Polyclonal Antibody
别名
TSPAN8; TM4SF3; Tetraspanin-8; Tspan-8; Transmembrane 4 superfamily member 3; Tumor-associated antigen CO-029
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7103
Human Swissprot No.
P19075
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P19075/entry
Mouse Swissprot No.
Q8R3G9
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R3G9
免疫原
The antiserum was produced against synthesized peptide derived from human TSPAN8. AA range:96-145
特异性
Tetraspanin-8 Polyclonal Antibody detects endogenous levels of Tetraspanin-8 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Gastric, colon, rectal, and pancreatic carcinomas.
细胞定位
Membrane; Multi-pass membrane protein.
功能
similarity:Belongs to the tetraspanin (TM4SF) family.,tissue specificity:Gastric, colon, rectal, and pancreatic carcinomas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
