产品名称
ACSS1 (Acetyl-K642) Rabbit Polyclonal Antibody
别名
Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1)
基因名称
ACSS1 ACAS2L KIAA1846
反应种属
Human:K642,Mouse:K635,Rat:K635
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84532
Human Swissprot No.
Q9NUB1
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9NUB1/entry
Mouse Swissprot No.
Q99NB1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q99NB1
免疫原
Synthesized Acetyl peptide derived from human ACSS1. at AA range: K642
特异性
This antibody detects endogenous levels of ACSS1 at Human:K642;Mouse:K635;Rat:K635, It doesn't reacte with total protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a mitochondrial acetyl-CoA synthetase enzyme. A similar protein in mice plays an important role in the tricarboxylic acid cycle by catalyzing the conversion of acetate to acetyl CoA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
组织表达
Amygdala,Brain,PCR rescued clones,Placenta,Spleen,Stomach,T
细胞定位
Mitochondrion matrix .
信号通路
Glycolysis / Gluconeogenesis;Pyruvate metabolism;Propanoate metabolism;
功能
catalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,function:Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2).,sequence caution:Sequencing errors.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
