产品名称
TCP-1 θ Rabbit Polyclonal Antibody
别名
CCT8; C21orf112; CCTQ; KIAA0002; T-complex protein 1 subunit theta; TCP-1-theta; CCT-theta; Renal carcinoma antigen NY-REN-15
蛋白名称
T-complex protein 1 subunit theta
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10694
Human Swissprot No.
P50990
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P50990/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12469
Mouse Swissprot No.
P42932
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P42932
免疫原
The antiserum was produced against synthesized peptide derived from human CCT8. AA range:361-410
特异性
TCP-1 θ Polyclonal Antibody detects endogenous levels of TCP-1 θ protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes the theta subunit of the CCT chaperonin, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins. Alternative splicing results in multiple transcript variants of this gene. A pseudogene related to this gene is located on chromosome 1. [provided by RefSeq, Sep 2013],
组织表达
Adipose tissue,B-cell lymphoma,Bone marrow,Chondrosarcoma,Epitheliu
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body .
功能
function:Molecular chaperone; assist the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.,similarity:Belongs to the TCP-1 chaperonin family.,subunit:Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
