产品名称
TCF-9 Rabbit Polyclonal Antibody
别名
GCFC2; C2orf3; GCF; TCF9; GC-rich sequence DNA-binding factor 2; GC-rich sequence DNA-binding factor; Transcription factor 9; TCF-9
蛋白名称
GC-rich sequence DNA-binding factor 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6936
Human Swissprot No.
P16383
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P16383/entry
Mouse Swissprot No.
Q8BKT3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BKT3
免疫原
The antiserum was produced against synthesized peptide derived from human GCF. AA range:141-190
特异性
TCF-9 Polyclonal Antibody detects endogenous levels of TCF-9 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008],
组织表达
Widely expressed in tissues and cell lines.
细胞定位
Nucleus, nucleoplasm . Nucleus, nucleolus .
信号通路
Stem cell pathway; Protein_Acetylation
功能
function:Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.,sequence caution:Contaminating sequence. The N-terminus matches the 2q37.3 region.,similarity:Belongs to the GCF family.,tissue specificity:Widely expressed in tissues and cell lines.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
