产品名称
TBX22 Rabbit Polyclonal Antibody
别名
TBX22; TBOX22; T-box transcription factor TBX22; T-box protein 22
蛋白名称
T-box transcription factor TBX22
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50945
Human Swissprot No.
Q9Y458
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y458/entry
Mouse Swissprot No.
Q8K402
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K402
免疫原
The antiserum was produced against synthesized peptide derived from human TBX22. AA range:1-50
特异性
TBX22 Polyclonal Antibody detects endogenous levels of TBX22 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
T-box 22(TBX22) Homo sapiens This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Seems to be expressed at a low level.
功能
disease:Defects in TBX22 are the cause of X-linked cleft palate with ankyloglossia (CPX) [MIM:303400].,function:Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Seems to be expressed at a low level.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
