产品名称
TBX2 Rabbit Polyclonal Antibody
别名
TBX2; T-box transcription factor TBX2; T-box protein 2
蛋白名称
T-box transcription factor TBX2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6909
Human Swissprot No.
Q13207
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q13207/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21385
Mouse Swissprot No.
Q60707
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q60707
免疫原
The antiserum was produced against synthesized peptide derived from human TBX2. AA range:251-300
特异性
TBX2 Polyclonal Antibody detects endogenous levels of TBX2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. [provided by RefSeq, Jul 2008],
组织表达
Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.
功能
function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
