产品名称
TCF-9 Rabbit Polyclonal Antibody
别名
GCFC2; C2orf3; GCF; TCF9; GC-rich sequence DNA-binding factor 2; GC-rich sequence DNA-binding factor; Transcription factor 9; TCF-9
蛋白名称
GC-rich sequence DNA-binding factor 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6936
Human Swissprot No.
P16383
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P16383/entry
Mouse Swissprot No.
Q8BKT3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BKT3
免疫原
The antiserum was produced against synthesized peptide derived from human GCF. AA range:141-190
特异性
TCF-9 Polyclonal Antibody detects endogenous levels of TCF-9 protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008],
组织表达
Widely expressed in tissues and cell lines.
细胞定位
Nucleus, nucleoplasm . Nucleus, nucleolus .
信号通路
Stem cell pathway; Protein_Acetylation
功能
function:Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.,sequence caution:Contaminating sequence. The N-terminus matches the 2q37.3 region.,similarity:Belongs to the GCF family.,tissue specificity:Widely expressed in tissues and cell lines.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
