产品名称
TAUT Rabbit Polyclonal Antibody
别名
SLC6A6; Sodium- and chloride-dependent taurine transporter; Solute carrier family 6 member 6
蛋白名称
Sodium- and chloride-dependent taurine transporter
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6533
Human Swissprot No.
P31641
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P31641/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21366
Mouse Swissprot No.
O35316
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35316
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29464
Rat Swissprot Link
http://www.uniprot.org/uniprot/P31643
免疫原
The antiserum was produced against synthesized peptide derived from human SLC6A6. AA range:561-610
特异性
TAUT Polyclonal Antibody detects endogenous levels of TAUT protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
组织表达
Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
function:Required for the uptake of taurine.,PTM:Down-regulated upon Ser-322 phosphorylation.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
