产品名称
TASK-5 Rabbit Polyclonal Antibody
别名
KCNK15; TASK5; Potassium channel subfamily K member 15; Acid-sensitive potassium channel protein TASK-5; TWIK-related acid-sensitive K(+) channel 5; Two pore potassium channel KT3.3; Two pore K(+) channel KT3.3
蛋白名称
Potassium channel subfamily K member 15
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=60598
Human Swissprot No.
Q9H427
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H427/entry
免疫原
The antiserum was produced against synthesized peptide derived from human KCNK15. AA range:273-322
特异性
TASK-5 Polyclonal Antibody detects endogenous levels of TASK-5 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
potassium two pore domain channel subfamily K member 15(KCNK15) Homo sapiens This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008],
组织表达
Detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland, and at lower levels in prostate, spleen and thyroid gland.
细胞定位
Membrane; Multi-pass membrane protein.
功能
function:Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel.,polymorphism:Three variant polypeptides are known: TASK-5A, TASK-5B and TASK-5C. The sequence shown is that of TASK-5C.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Heterodimer .,tissue specificity:Detected in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland, and at lower levels in prostate, spleen and thyroid gland.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
