产品名称
TALK-2 Rabbit Polyclonal Antibody
别名
KCNK17; TALK2; TASK4; Potassium channel subfamily K member 17; 2P domain potassium channel Talk-2; Acid-sensitive potassium channel protein TASK-4; TWIK-related acid-sensitive K(+) channel 4; TWIK-related alkaline pH-activated K(+) channel
蛋白名称
Potassium channel subfamily K member 17
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=89822
Human Swissprot No.
Q96T54
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96T54/entry
免疫原
The antiserum was produced against synthesized peptide derived from human KCNK17. AA range:271-320
特异性
TALK-2 Polyclonal Antibody detects endogenous levels of TALK-2 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
potassium two pore domain channel subfamily K member 17(KCNK17) Homo sapiens The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],
组织表达
Adrenal gland,Lung,Pancreas,Spleen,
细胞定位
Membrane; Multi-pass membrane protein.
功能
function:Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.,miscellaneous:Inhibited by Ba(2+), quinidine, chloroform and halothane. Activated at alkaline pH. Activated by quinine and isoflurane.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
